Based in New York, Diller Scofidio + Renfro is an interdisciplinary design studio whose practice spans the fields of architecture, urban design, digital media, installation art, and multimedia performance. Partners Elizabeth Diller, Ricardo Scofidio, Charles Renfro, and Benjamin Gilmartin focus on cultural and civic projects and address the changing role of institutions and the future of cities. This issue features an interview with the four partners and takes stock of their work since 2000, focusing on major projects such as the High Line and The Shed in New York, Zaryadye Park in Moscow, the Museum of Image and Sound in Rio de Janeiro, London Centre for Music, and more.